Shit on (shingles) ..

 Shit on (shingles) 

Biscuits and Gravy  

Most medications should be stored at room temperature (59°F to 77°F). While many medications require refrigeration (36°F to 46°F), freezing is dangerous for most drugs as it destroys their chemical structure or physical stability. 

Baystate Health

 +2

However, a select few specific medications actively require frozen storage (usually between -13°F and 5°F). 

Medications That Require a Freezer

Most of these are highly sensitive biologicals, vaccines, or specific suppositories:

Vaccines: Varicella (chickenpox) and Zoster (shingles) vaccines.

Hormonal Inserts: Dinoprostone vaginal inserts (Cervidil) and suppositories (Prostin E2).

Specialized Medications: Anthrax immune globulin (Anthrasil) and Carmustine wafers (Gliadel). 

IEHP

 +1

Medications That MUST Be Refrigerated (But NOT Frozen)

Many medications need to be kept cold, but will be ruined if they freeze. Examples include: 

GoodRx

 +2

Insulin: All forms.

GLP-1s & Biologics: Ozempic, Humira, Enbrel, and Copaxone.

Eye Drops: Many prescription drops, especially for glaucoma (e.g., Latanoprost).

Liquid Antibiotics: Such as Amoxicillin (once mixed by the pharmacy).

Other Injectables: Fertility medications (Gonal-f, Follistim) and growth hormones. 

GoodRx

 +4

What if your medicine froze?

If any medication that is not meant to be frozen experiences a solid freeze, it is generally no longer safe or effective to use. Some suspensions separate, and proteins in biologics can break down. 

Baystate Health

 +3

Because you cannot always see physical changes, use the GoodRx Medication Finder to read up on your specific product, or contact a local pharmacist to see if a frozen medication needs to be replaced